Narrative Highlight: Carl Kjellstrand

Narrative Highlight: Carl Kjellstrand

At part of the 50th Anniversary meeting of ASAIO we conducted preliminary exchanges with individuals working in the field of artificial organs. The text below comes from Carl Kjellstrand, MD, PhD.

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1. Which individual or event do you attribute the greatest historical significance in the advancement of organ replacement devices or machines? Please explain why.

Artificial Kidney

- Basics: (1) Thomas Graham for the separation of molecules; (2) Hid. Marin Roudle for discovering urea in urine; (3) Claude Bernard for the interiour milieau main function of kidneys.

- First Steps: (4a) Abel, Rountree, Turner in 1913 for first in vivo dialysis; (4b) Necheles for flat plate; (5) Haas in 1925 for first dialysis of human.

- Technical Solutions: (6) Kolff for rotating drum kidney in 1943; (7) Alwall for stationary drum and ultrafilter in 1946; (8) Murray for stationary drum in Canada in 1946.

- There was then Resistance to Innovations.