The Summer 2003 edition marks the 20th anniversary of Issues in Science & Technology, and we have prepared a special issue to celebrate. We reviewed our archives and selected what might be considered our greatest hits—first-rate authors writing about the most important subjects. We asked each of these authors to revisit the original topic and update readers on what is happening. The result is a panoramic view of science, technology, and health policy by many of the nation's leading experts, including Anthony Fauci, David Baltimore, Daniel Yankelovich, and E.O. Wilson. The entire anniversary issue is dedicated to these updates, and we have posted all the original articles on our website. Please join us in celebrating and learning from 20 years of Issues